Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 15/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359317 | 0.84 | GRIA2 (0.71) | GRIA2CA1CA2GRIA1GRIA3 | |
| SCHEMBL22823720 | 0.84 | GRIA2 (1.00) | GRIA2CA1CA2GRIA1GRIA3 | |
| SCHEMBL32682813 | 0.84 | GRIA2 (1.00) | GRIA2CA1CA2GRIA1GRIA3 | |
| SCHEMBL6494353 | 0.84 | GRIA2 (0.70) | GRIA2CA1CA2GRIA1GRIA3 | |
| SCHEMBL5184614 | 0.84 | GRIA2 (0.70) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL6504948 | 0.84 | GRIA2 (0.70) | GRIA2CA1CA2GRIA1GRIA3 | |
| SCHEMBL5619678 | 0.82 | GRIA2 (0.73) | GRIA2 | |
| SCHEMBL6413657 | 0.81 | GRIA2 (0.67) | GRIA2 | |
| SCHEMBL5418711 | 0.80 | GRIA2 (0.64) | GRIA2CA1CA2 | |
| SCHEMBL6495909 | 0.80 | GRIA2 (0.72) | GRIA2CA1CA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894043-B1 | Benzothiadiazine derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-05-17 | — | — | US | disclosed |
| CN-1162414-C | Benzothiadiazine derivs., preparation method and pharmaceutical compositions contg. same | ɪά��ʵ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-1233953-B1 | NOVEL BENZOTHIADIAZINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-05-14 | — | — | EP | disclosed |
| CN-1402717-A | Benzothiadiazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-12 | — | — | CN | disclosed |