Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414665 | 0.86 | DDX3X (0.53) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL6419686 | 0.84 | DHODH (0.47) | DHODHCYP2C19ALDH1A1POLBMAPT | |
| SCHEMBL6433093 | 0.83 | GAA (0.45) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL6416062 | 0.81 | BIRC5 (0.46) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL6415725 | 0.80 | GAA (0.51) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL6414142 | 0.79 | MAPT (0.43) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL6413685 | 0.79 | MAPT (0.51) | CYP2C19ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6413690 | 0.79 | MAPT (0.51) | CYP2C19ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6417113 | 0.78 | DDX3X (0.57) | CYP2C19ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6417108 | 0.78 | DDX3X (0.57) | CYP2C19ALDH1A1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | 4SC AG (DE) | 2005-06-30 | — | — | US | disclosed |
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143382-A1 | Heterocyclic compounds as pharmaceutically active compounds | NR5A2, NR1H2, NR2C2 | DHODH 1369/4885KDM5B 2671/4885CYP2C19 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.