Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Anisole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.88 |
| ▸ | LTA4H | P09960 | 3/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL28062631 | 1.00 | CA4 (0.88) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL7554435 | 0.94 | CA4 (0.88) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL14954294 | 0.94 | CA4 (0.88) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL28012985 | 0.94 | CA4 (0.88) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL14954300 | 0.94 | CA4 (0.88) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL20328417 | 0.94 | — | — | |
| Anisole SCHEMBL1205 | 0.94 | — | — | |
| Anisole SCHEMBL28813915 | 0.94 | CA4 (1.00) | CA4LTA4HCA1CA2CA7 | |
| Anisole SCHEMBL30601749 | 0.94 | — | — | |
| Anisole SCHEMBL2493788 | 0.94 | CA4 (1.00) | CA4LTA4HCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122628-A1 | IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE CEFOTETAN DISODIUM | LUPIN LIMITED (IN) | 2007-11-01 | — | — | WO | claimed |
| EP-4370507-A1 | HYDROGENATED QUINOXALINES | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| CN-117616013-A | Hydrogenated quinoxalines | 大塚制药株式会社 | 2024-02-27 | — | — | CN | disclosed |
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |
| CN-105481848-A | Cefotetan active ester and high purity cefotetan acid preparation method | CHONGQINGG TIANDI PHARMACEUTICAL CO LTD CHINA | 2016-04-13 | — | — | CN | disclosed |
| CN-103524449-B | Method for synthesizing 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-103524449-A | Method for synthesizing 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| US-8541573-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8318769-B2 | Substituted sulfonamide compounds | GRUENETHAL GMBH (DE) | 2012-11-27 | — | — | US | disclosed |
| CN-102718780-A | Preparation method of cefmetazole sodium | WEINA LIU | 2012-10-10 | — | — | CN | disclosed |
| WO-1993003042-A1 | 6-ETHYLIDENE PENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |
| EP-0430037-A2 | Process for producing 2-carbon-substituted carbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4931434-A | Penem compounds | BEECHAM GROUP P.L.C. (GB) | 1990-06-05 | — | — | US | disclosed |
| EP-0321187-A1 | 6-(Substituted methylene)penems | BEECHAM GROUP PLC (GB) | 1989-06-21 | — | — | EP | disclosed |
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| CN-85105749-A | The method for preparing cephalosporin antibiotic | — | 1986-12-31 | — | — | CN | disclosed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |
| US-4376770-A | OXACEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1983-03-15 | — | — | US | disclosed |
| US-4135045-A | PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-4048415-A | TITANIUM-ALUMINUM COORDINATION CATALYSTS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) | 1977-09-13 | — | — | US | disclosed |