SCHEMBL6414916

SCHEMBL6414916

CCCCCCCCCC[SiH](C)O[SiH3]

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 7/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1464491 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6907097 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL839006 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1425732 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3220225 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5694917 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9311539 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL595849 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7602533 0.97
SCHEMBL4739965 0.95 TSHR (0.38) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118179275-A Preparation method and application of silicone rubber composite separation membrane 中国科学院大连化学物理研究所 2024-06-14 CN claimed
US-20050222323-A1 Thermally conductive coating compositions, methods of production and uses thereof HONEYWELL INTERNATIONAL INC. 2005-10-06 US claimed
WO-2003088315-A2 THERMALLY CONDUCTIVE COATING COMPOSITIONS, METHODS OF PRODUCTION AND USES THEREOF HONEYWELL INTERNATIONAL INC. (US) 2003-10-23 WO claimed
US-4486325-A CHLOROPHENYL TRIALKOXYSILANE AS DOPANT RCA CORPORATION (US) 1984-12-04 US claimed
US-4456636-A BY DISSOLVING IN BUTANOL RCA CORPORATION (US) 1984-06-26 US claimed
US-3933678-A Optically clear organosilicon compounds DOW CORNING CORPORATION (US) 1976-01-20 US claimed
CN-118179275-A Preparation method and application of silicone rubber composite separation membrane 中国科学院大连化学物理研究所 2024-06-14 CN disclosed
CN-112088205-B Lubricating oil composition and lubricant using same 株式会社MORESCO 2022-11-08 CN disclosed
US-20050222323-A1 Thermally conductive coating compositions, methods of production and uses thereof HONEYWELL INTERNATIONAL INC. 2005-10-06 US disclosed
US-4560601-A MIXTURE OF POLYPHENYLENE ETHER DONOR AND ACCEPTOR RCA CORPORATION (US) 1985-12-24 US disclosed
US-4540615-A CAPACITANCE, TETRAPHENYLSILOXANE RCA CORPORATION (US) 1985-09-10 US disclosed
US-4525402-A SILOXANES WITH TITANIUM COUPLING AGENT RCA CORPORATION (US) 1985-06-25 US disclosed
US-4486325-A CHLOROPHENYL TRIALKOXYSILANE AS DOPANT RCA CORPORATION (US) 1984-12-04 US disclosed
US-4444820-A POLYSILOXANE WITH 9-PHENYLSTEARYL ALCOHOL RCA CORPORATION (US) 1984-04-24 US disclosed
US-4416789-A METHYL ALKYL SILOXANE WITH ALKYL SUBSTITUTED BETAINE RCA CORPORATION (US) 1983-11-22 US disclosed
US-4342659-A Video disc lubricants RCA CORPORATION (US) 1982-08-03 US disclosed
US-4330583-A COATING OF HYDROXYLATED AMINE AND POLYSILOXANE OR SILICON-CONTAINING COMPOUND; ANTIDEPOSIT AGENTS; TELEVISION; AUDIO DEVICES RCA CORPORATION (US) 1982-05-18 US disclosed
US-4275101-A METHYL ALKYL SILOXANE PROVIDES STORAGE STABILITY RCA CORPORATION (US) 1981-06-23 US disclosed
US-3933678-A Optically clear organosilicon compounds DOW CORNING CORPORATION (US) 1976-01-20 US disclosed
US-3933678-A Optically clear organosilicon compounds DOW CORNING CORPORATION (US) 1976-01-20 US disclosed