SCHEMBL6907097

SCHEMBL6907097

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC[SiH](C)O[SiH3]

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 7/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1464491 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL839006 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1425732 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3220225 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5694917 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9311539 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6414916 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL595849 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7602533 0.97
SCHEMBL4739965 0.95 TSHR (0.38) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115799-B1 CURABLE SILICONE FOUL RELEASE COATINGS AND ARTICLES GEN ELECTRIC (US) 2004-10-13 EP disclosed
US-6403105-B1 COMPATIBLE SILICONE FLUID FREE FROM SILANOL GROUPS AND BEING CAPABLE OF BLOOMING TO THE SURFACE OF THE CURED SILOXANE GENERAL ELECTRIC COMPANY 2002-06-11 US disclosed
EP-1115799-A1 CURABLE SILICONE FOUL RELEASE COATINGS AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2001-07-18 EP disclosed
US-6180249-B1 RTV POLYORGANOSILOXANE AND (B) A MARINE FOUL RELEASE-ENHANCING PROPORTION OF A COMPATIBLE SILICONE FLUID FREE FROM SILANOL GROUPS AND BEING CAPABLE OF BLOOMING TO THE SURFACE OF THE CURED PRODUCT GENERAL ELECTRIC COMPANY 2001-01-30 US disclosed
US-6084049-A FUSER ROLL WITH A HEAT STABLE TRIMETHYLSILANOL-ENDCAPPED POLYSILOXANE ON THE SURFACE THEREOF EFFECTIVE FOR RELEASE OF TONER; MELTING POINT SUCH THAT IT IS LIQUID ON THE HOT FUSER ROLL, BUT SOLIDIFIES AT ROOM TEMPERATURE ON THE PRINTED PAGE LEXMARK INTERNATIONAL, INC. (US) 2000-07-04 US disclosed
WO-2000014166-A1 CURABLE SILICONE FOUL RELEASE COATINGS AND ARTICLES GENERAL ELECTRIC COMPANY (US) 2000-03-16 WO disclosed