Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155281 | 0.83 | PNMT (0.62) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL27753726 | 0.82 | PNMT (0.53) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL30606684 | 0.80 | PNMT (0.68) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL633763 | 0.80 | PNMT (0.68) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL7195192 | 0.80 | PNMT (0.72) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL5366733 | 0.80 | PNMT (0.72) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL28483707 | 0.79 | PNMT (0.57) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL3679006 | 0.78 | PNMT (0.49) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL7609046 | 0.78 | PNMT (0.70) | PNMTDRD2DRD3DRD4NPC1 | |
| SCHEMBL7603814 | 0.78 | PNMT (0.70) | PNMTDRD2DRD3DRD4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489082-B1 | Intermediate compounds | ZOETIS P & U LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-0871631-B1 | ANTIPARASITIC MARCFORTINES AND PARAHERQUAMIDES | PHARMACIA & UPJOHN CO LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1489082-A1 | Intermediate compounds | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-0963990-B1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2004-10-06 | — | — | EP | disclosed |
| EP-1400523-A2 | Intermediate compounds | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-24 | — | — | EP | disclosed |
| US-6197990-B1 | REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0963990-A1 | PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5750695-A | Antiparasitic paraherquamides | PHARMACIA & UPJOHN COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5703078-A | ANTIBIOTICS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |