SCHEMBL6415260

SCHEMBL6415260

O=C(NCCO)c1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCOc1ccc(C(F)(F)F)cn1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 16/20 0.44
SCN10A Q9Y5Y9 3/20 0.39
PPARD Q03181 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
P2RX7 Q99572 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
SCN7A Q01118 1/20 0.36
KCNH2 Q12809 1/20 0.36
SCN5A Q14524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408724 0.87 MRGPRX4 (0.40) SCN9ASCN10APPARDMRGPRX4
SCHEMBL6417301 0.86 LMNA (0.42) SCN9ASCN10AMRGPRX4
SCHEMBL4625368 0.86 GSTP1 (0.36) SCN9ASCN10APPARDMRGPRX4
Pyridalyl SCHEMBL83386 0.85 KMT2A (0.39) SCN9ASCN10AMRGPRX4
Pyridalyl SCHEMBL29354972 0.85 KMT2A (0.39) SCN9ASCN10AMRGPRX4
SCHEMBL4624453 0.85 MRGPRX4 (0.38) SCN9ASCN10AMRGPRX4
SCHEMBL7076327 0.83 KMT2A (0.39) SCN9AMRGPRX4
SCHEMBL7965974 0.83 SCN9A (0.46) SCN9ASCN10APPARDSCN7AKCNH2
SCHEMBL4624909 0.82 KMT2A (0.36) SCN9ASCN10AMRGPRX4
SCHEMBL7074999 0.82 KMT2A (0.39) SCN9AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949551-B2 Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides BAYER CROPSCIENCE S.A. (FR) 2005-09-27 US disclosed
US-20040029886-A1 Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides MERIAL, INC. 2004-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029886-A1 Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides DDT, CBR1, CBR3 SCN9A 284/4885SCN10A 417/4885PPARD 2619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.