Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003720 | 0.88 | TSHR (0.50) | TSHRCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL9321534 | 0.81 | CYP3A4 (0.40) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL9771559 | 0.81 | CYP3A4 (0.40) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL10999631 | 0.81 | TSHR (0.46) | TSHRCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11264306 | 0.79 | CYP3A4 (0.39) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL7930064 | 0.79 | TSHR (0.44) | TSHRCYP3A4MAPK1TDP1LMNA | |
| SCHEMBL11521783 | 0.79 | CYP3A4 (0.39) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL2421869 | 0.79 | MAPK1 (0.44) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL11540837 | 0.79 | CYP3A4 (0.39) | TSHRCYP3A4MAPK1TDP1AHR | |
| SCHEMBL2262591 | 0.78 | TSHR (0.46) | TSHRCYP3A4MAPK1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433069-A | Preparation method of 2, 4-dichlorobenzaldehyde | 柳州东风容泰化工股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-113896652-A | Preparation method of 3, 4-dichlorobenzonitrile | 江苏超跃化学有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113582836-A | Method for synthesizing 2, 4-dichlorobenzoyl chloride | 江苏超跃化学有限公司 | 2021-11-02 | — | — | CN | claimed |
| EP-1528052-A1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA S.p.A. (IT) | 2005-05-04 | — | — | EP | claimed |
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | claimed |
| CN-115433069-A | Preparation method of 2, 4-dichlorobenzaldehyde | 柳州东风容泰化工股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113896652-A | Preparation method of 3, 4-dichlorobenzonitrile | 江苏超跃化学有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113896652-A | Preparation method of 3, 4-dichlorobenzonitrile | 江苏超跃化学有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113582836-A | Method for synthesizing 2, 4-dichlorobenzoyl chloride | 江苏超跃化学有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-109678698-B | Preparation method of 2, 4-dichlorobenzoyl chloride | 江苏佳麦化工有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113582836-A | Method for synthesizing 2, 4-dichlorobenzoyl chloride | 江苏超跃化学有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113387812-A | Process for preparing (hetero) aromatic polyamines | 深圳有为技术控股集团有限公司 | 2021-09-14 | — | — | CN | disclosed |
| US-4283565-A | REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY | DYNAMIT NOBEL AG (DE) | 1981-08-11 | — | — | US | disclosed |
| EP-0021520-A1 | (Cycloalkyl)alkoxyimino-substituted cyclopropanecarboxylate esters, process for their manufacture, pesticidal compositions containing them, and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-01-07 | — | — | EP | disclosed |
| US-4219565-A | INSECTICIDES, MITICIDES | SHELL OIL COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
| US-4141912-A | Process for the preparation of polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4075238-A | Polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4039587-A | Method of preparing polynuclear, halogenated, aromatic benzyl ethers | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4000052-A | METHOD OF PREPARING METHYLCHLOROMETHYLTETRACHLOROBENZENES AND DI-(CHLOROMETHYL)-TETRACHLOROBENZENES | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3994922-A | Benzopyrans and intermediates for the preparation of pyrrolo benzopyrans | ARTHUR D. LITTLE, INC. (US) | 1976-11-30 | — | — | US | disclosed |