Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415554 | 1.00 | CCR5 (0.60) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6429897 | 0.99 | CCR5 (0.59) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6410803 | 0.99 | CCR5 (0.59) | CCR5KCNH2 | |
| SCHEMBL6417677 | 0.97 | CCR5 (0.63) | CCR5KCNH2 | |
| SCHEMBL6417679 | 0.97 | CCR5 (0.63) | CCR5KCNH2 | |
| SCHEMBL6409249 | 0.96 | CCR5 (0.62) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6411417 | 0.96 | CCR5 (0.62) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6411408 | 0.96 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL6409254 | 0.96 | CCR5 (0.62) | CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL6416591 | 0.95 | CCR5 (0.61) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA INC (CA) | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | CXCR1, CXCR4, CXCR2 | CCR5 4/4885KCNH2 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.