Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | LDHA | P00338 | 6/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415953 | 1.00 | BIRC5 (0.67) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6415088 | 0.93 | BIRC5 (0.57) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6415091 | 0.93 | BIRC5 (0.57) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6419742 | 0.93 | BIRC5 (0.69) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6419739 | 0.93 | BIRC5 (0.69) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6414867 | 0.91 | BIRC5 (0.54) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6414866 | 0.91 | BIRC5 (0.54) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6431827 | 0.90 | BIRC5 (0.70) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6431818 | 0.90 | BIRC5 (0.70) | BIRC5KDM4EMAPTGAARAB9A | |
| SCHEMBL6434884 | 0.90 | BIRC5 (0.71) | BIRC5KDM4EMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |