SCHEMBL6416432

SCHEMBL6416432

CCOC(=O)/C(C/C(C)=N\O)=N\O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
MAPT P10636 1/20 0.44
GLO1 Q04760 1/20 0.44
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 5/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
EGLN1 Q9GZT9 1/20 0.37
KYAT1 Q16773 5/20 0.37
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6416435 1.00 APOBEC3A (0.50) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL20924984 0.82 GAA (0.56) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL20912999 0.82 GAA (0.56) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL5390862 0.82 MAPT (0.46) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL20912998 0.82 GAA (0.56) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL7645072 0.79 APOBEC3A (0.57) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL28622235 0.79 APOBEC3A (0.51) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL26325159 0.79 APOBEC3A (0.51) APOBEC3AAPOBEC3GMAPTGLO1NPSR1
SCHEMBL11415476 0.77 APOBEC3A (0.51) APOBEC3AAPOBEC3GMAPTALDH1A1LMNA
SCHEMBL11415472 0.77 APOBEC3A (0.51) APOBEC3AAPOBEC3GMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050130989-A1 N-arylheteroaromatic products compositions containing them and use thereof AVENTIS PHARMA S. A. (FR) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050130989-A1 N-arylheteroaromatic products compositions containing them and use thereof AHR, NQO1, ARNT APOBEC3A 1121/4885APOBEC3G 763/4885MAPT 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.