Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.62 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451864 | 0.85 | PTGER4 (0.58) | PTGER4PTGER3PTGER2PTGER1CYSLTR2 | |
| SCHEMBL11885012 | 0.81 | PTGER4 (0.47) | PTGER4PTGER3PTGER2PTGER1CYP4F2 | |
| SCHEMBL1454107 | 0.78 | PTGER1 (0.49) | PTGER4PTGER3PTGER2PTGER1CYSLTR2 | |
| SCHEMBL16961333 | 0.77 | PTGER4 (0.41) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL3673001 | 0.77 | HDAC3 (0.57) | PTGER4PTGER3PTGER2PTGER1CYSLTR2 | |
| SCHEMBL16954557 | 0.77 | MAPT (0.44) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7955267 | 0.77 | PTGER4 (1.00) | PTGER4PTGER3PTGER2PTGER1THRA | |
| SCHEMBL9863165 | 0.76 | HDAC3 (0.55) | PTGER4PTGER3PTGER2PTGER1CYSLTR2 | |
| SCHEMBL9863168 | 0.76 | HDAC3 (0.55) | PTGER4PTGER3PTGER2PTGER1CYSLTR2 | |
| SCHEMBL23964581 | 0.75 | PTGER4 (0.60) | PTGER4PTGER3PTGER2PTGER1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887670-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-05-03 | — | — | US | disclosed |