Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 10/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 10/20 | 1.00 |
| ▸ | PTGER2 | P43116 | 9/20 | 1.00 |
| ▸ | PTGER1 | P34995 | 6/20 | 1.00 |
| ▸ | THRA | P10827 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807171 | 0.85 | PTGER4 (0.73) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7798336 | 0.80 | PTGER3 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7798340 | 0.80 | PTGER3 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7805997 | 0.80 | PTGER4 (0.73) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7959162 | 0.78 | PTGER3 (0.72) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7961858 | 0.77 | PTGER4 (0.62) | PTGER4PTGER3PTGER2PTGER1THRA | |
| SCHEMBL7961865 | 0.77 | PTGER4 (0.69) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL7947922 | 0.77 | PTGER3 (0.82) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL6416631 | 0.77 | PTGER4 (0.62) | PTGER4PTGER3PTGER2PTGER1THRA | |
| SCHEMBL7961856 | 0.76 | PTGER3 (0.80) | PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031766-A1 | Prostaglandin receptor ligands | MERCK FROSST CANADA & CO. | 2001-10-18 | — | — | US | disclosed |
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031766-A1 | Prostaglandin receptor ligands | PTGER1, PTGER2, PTGFR | PTGER4 11/4885PTGER3 9/4885PTGER2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.