Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 1.00 |
| ▸ | PRKCG | P05129 | 15/20 | 1.00 |
| ▸ | PRKCB | P05771 | 15/20 | 1.00 |
| ▸ | PRKCA | P17252 | 14/20 | 1.00 |
| ▸ | CDK1 | P06493 | 3/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 2/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 6/20 | 0.85 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.81 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.80 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.80 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.80 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.80 |
| ▸ | PRKACA | P17612 | 1/20 | 0.80 |
| ▸ | PRKACG | P22612 | 1/20 | 0.80 |
| ▸ | PRKACB | P22694 | 1/20 | 0.80 |
| ▸ | KDR | P35968 | 1/20 | 0.80 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.80 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.80 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345338 | 1.00 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| Indolylylmaleimide 2 SCHEMBL4341971 | 1.00 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4342534 | 1.00 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL22765525 | 0.99 | GSK3B (0.97) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL25778145 | 0.95 | GSK3B (0.90) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4344559 | 0.92 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4336077 | 0.90 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4344077 | 0.89 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4351003 | 0.89 | PRKCG (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 | |
| SCHEMBL4346022 | 0.89 | GSK3B (1.00) | GSK3BPRKCGPRKCBPRKCACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2664669-B1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH INC (US) | 2017-12-27 | — | — | EP | disclosed |
| EP-2664669-A1 | Treatment of pluripotent cells | Janssen Biotech, Inc. (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-1345946-B1 | MACROHETEROCYLIC COMPOUNDS USEFUL AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2005-08-10 | — | — | EP | disclosed |