SCHEMBL6417624

SCHEMBL6417624

CCCCCCCCCCC(CCCCCCCCCC)NC(CC)[Si](OC)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.36
PLA2G2A P14555 1/20 0.33
LMNA P02545 1/20 0.31
PLA2G2C Q5R387 1/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
EPHX1 P07099 1/20 0.30
DNM1 Q05193 1/20 0.30
SMPD1 P17405 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992812 0.87 ZDHHC7 (0.37) ZDHHC7LMNAADH1BADH1CADH1A
SCHEMBL28992804 0.85 ZDHHC7 (0.34) ZDHHC7CA1CA2
SCHEMBL28992776 0.81 ZDHHC7 (0.33) ZDHHC7
SCHEMBL1038513 0.81 OPRM1 (0.36) ZDHHC7PLA2G2ALMNACA1CA2
SCHEMBL28992770 0.79 ZDHHC7 (0.31) ZDHHC7
SCHEMBL28992782 0.78 ZDHHC7 (0.33) ZDHHC7
SCHEMBL56081 0.76
SCHEMBL21750612 0.75 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1
SCHEMBL22721264 0.75 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1
SCHEMBL28510570 0.75 ZDHHC7 (0.37) ZDHHC7LMNADNM1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050214236-A1 Surface treated pearlescent pigments for hair care products MARCK PATENT GMBH (DE) 2005-09-29 US disclosed