Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20811620 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL38017 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL17760125 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL192501 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL2489604 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL192921 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL1853822 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL29038999 | 1.00 | HSD17B10 (0.42) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL1334717 | 0.87 | NR1H2 (0.39) | HSD17B10NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL15116701 | 0.87 | NR1H2 (0.39) | HSD17B10NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539118-A | Novel process for synthesizing N-Boc-4-fluoro-L-proline | 南京碳硅人工智能生物医药技术研究院有限公司 | 2022-05-27 | — | — | CN | claimed |
| WO-2026085629-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2026-04-30 | — | — | WO | disclosed |
| US-20250171400-A1 | AZA-HETEROCYCLYL CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | X-BIOTIX THERAPEUTICS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-12227475-B2 | Aza-heterocyclyl carboxamide and related compounds and their use in treating medical conditions | X-BIOTIX THERAPEUTICS, INC. | 2025-02-18 | — | — | US | disclosed |
| CN-119173253-A | Combination of allosteric and orthosteric EGFR inhibitors for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118525022-A | Azacyclo derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118339153-A | Heteroaromatic compounds for the treatment of cancer | 勃林格殷格翰国际有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114573491-B | Process for preparing pyrrolidine amide derivatives | 广东东阳光药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-4255908-A1 | NEW INDAZOLE ACETYLENE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| EP-4255906-A1 | NEW INDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| US-20120295884-A1 | Complement pathway modulators and uses thereof | NOVARTIS AG (CH) | 2012-11-22 | — | — | US | disclosed |
| WO-2012093101-A1 | INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) | NOVARTIS AG (CH) | 2012-07-12 | — | — | WO | disclosed |
| EP-2464368-A1 | CATHEPSIN C INHIBITORS | Glaxo Group Limited (GB) | 2012-06-20 | — | — | EP | disclosed |
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| WO-2012018534-A2 | SUBSTITUTED BIPHENYLENE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | SCHERING CORPORATION (US) | 2012-02-09 | — | — | WO | disclosed |
| US-20110281870-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2011-11-17 | — | — | US | disclosed |
| EP-2380892-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING PROLINE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-10-26 | — | — | EP | disclosed |
| JP-2011121872-A | METHOD FOR PURIFYING OPTICALLY ACTIVE N-TERT-BUTOXYCARBONYL-TRANS-4-FLUOROPROLINE | CENTRAL GLASS CO LTD | 2011-06-23 | — | — | JP | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | HSD17B10 3111/4885NR1H2 1408/4885CHRM2 309/4885 |
| US-12227475-B2 | Aza-heterocyclyl carboxamide and related compounds and their use in treating medical conditions | AADAC, AZI2, CBX7 | HSD17B10 2552/4885NR1H2 1699/4885CHRM2 3491/4885 |
| US-20110281870-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | CACNA1C, ORAI1, CACNA1S | HSD17B10 2971/4885NR1H2 2033/4885CHRM2 115/4885 |
| US-20120295884-A1 | Complement pathway modulators and uses thereof | C5, C3AR1, C9 | HSD17B10 2666/4885NR1H2 1256/4885CHRM2 945/4885 |
| US-20250171400-A1 | AZA-HETEROCYCLYL CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | AADAC, AZI2, CBX7 | HSD17B10 2552/4885NR1H2 1699/4885CHRM2 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.