Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409041 | 0.84 | TP53 (0.36) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL12951567 | 0.77 | TP53 (0.60) | TP53TSHRALDH1A1 | |
| SCHEMBL17201489 | 0.76 | TP53 (0.41) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL17795738 | 0.76 | TP53 (0.41) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL9746944 | 0.76 | TP53 (0.41) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL25107003 | 0.76 | TP53 (0.41) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL8036456 | 0.76 | TP53 (0.41) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL16074874 | 0.75 | TSHR (0.44) | TSHRTDP1 | |
| SCHEMBL5065017 | 0.74 | TP53 (0.39) | TP53TSHRCA2MAPK1CHRM1 | |
| SCHEMBL3500900 | 0.73 | TP53 (0.36) | TP53CA2MAPK1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602727-A2 | Novel erythromycins and process for their preparation | Biotica Technology Limited (GB) | 2005-12-07 | — | — | EP | disclosed |
| EP-0909327-B1 | ERYTHROMYCINS AND PROCESS FOR THEIR PREPARATION | BIOTICA TECH LTD (GB) | 2005-06-01 | — | — | EP | disclosed |