SCHEMBL6418982

SCHEMBL6418982

N#C/C(=C(\C#N)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 4/20 0.45
POLB P06746 1/20 0.44
ESR1 P03372 1/20 0.41
TSHR P16473 3/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
C1S P09871 1/20 0.40
PRSS3 P35030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79975 1.00 KMT2A (0.52) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL1898420 1.00 KMT2A (0.52) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL5189613 0.97 KMT2A (0.55) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL1712503 0.90 KMT2A (0.46) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL27929354 0.88 KMT2A (0.44) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL28310324 0.87 KMT2A (0.47) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL1343904 0.87 ESR1 (0.53) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL61242 0.87 MEN1 (0.68) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL15306805 0.86 CES2 (0.54) KMT2AMEN1ALDH1A1POLBESR1
SCHEMBL8544848 0.85 KMT2A (0.46) KMT2AMEN1ALDH1A1POLBESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260057-B Improved method for preparing functionalized cis-trans dicyanoethylene compound through desulfurization of 2, 5-dinitrothiophene 中国科学院大学 2023-07-25 CN disclosed
CN-115260057-A Improved method for preparing functionalized cis-trans dicyanoethylene compound by 2,5-dinitrothiophene desulfurization 中国科学院大学 2022-11-01 CN disclosed
US-9086640-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-07-21 US disclosed
US-20140065530-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-03-06 US disclosed
EP-2703889-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-03-05 EP disclosed
EP-1212384-A4 SELECTIVELY LIGHT-ABSORPTIVE MATERIAL, COATING COMPOSITION CONTAINING THE SAME, AND FILTER MANUFACTURED USING THE COATING COMPOSITION FOR COLOR DISPLAYS SKC CO LTD (KR) 2005-03-23 EP disclosed
US-6824712-B1 Selectively light-absorptive material, coating composition containing the same, and filter manufactured using the coating composition for color displays SKC CO. LTD. (CN) 2004-11-30 US disclosed
EP-1212384-A1 SELECTIVELY LIGHT-ABSORPTIVE MATERIAL, COATING COMPOSITION CONTAINING THE SAME, AND FILTER MANUFACTURED USING THE COATING COMPOSITION FOR COLOR DISPLAYS SKC Co., Ltd. (KR) 2002-06-12 EP disclosed
WO-2001010971-A1 SELECTIVELY LIGHT-ABSORPTIVE MATERIAL, COATING COMPOSITION CONTAINING THE SAME, AND FILTER MANUFACTURED USING THE COATING COMPOSITION FOR COLOR DISPLAYS SKC CO., LTD. (KR) 2001-02-15 WO disclosed
US-6074792-A CHARGE TRANSPORT LAYER AND CHARGE GENERATING LAYER RICOH COMPANY, LTD. (JP) 2000-06-13 US disclosed