Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1669641 | 0.79 | DRD1 (0.43) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL7238863 | 0.76 | AKR1C3 (0.41) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL8142884 | 0.69 | CYP2C19 (0.44) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL4739953 | 0.69 | AKR1C3 (0.44) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL2913672 | 0.67 | DRD1 (0.44) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL21113562 | 0.66 | DRD1 (0.43) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| Lithium SCHEMBL29926457 | 0.66 | DRD1 (0.43) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL1986102 | 0.66 | ABCB11 (0.46) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| Hydrochloric Acid SCHEMBL6615615 | 0.65 | DRD1 (0.45) | DRD1CYP2C19DRD4DRD3ABCB11 | |
| SCHEMBL28921395 | 0.64 | DRD4 (0.47) | DRD1CYP2C19DRD4DRD3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049415-A1 | Process for preparing enantiomerically pure alpha phenyl-alpha (6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)-acetic acid derivatives | MERCK GENERICS (UK) LIMITED (GB) | 2005-03-03 | — | — | US | disclosed |
| EP-1438314-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE ALPHA-PHENYL-APLPHA(6,7-DIHYDRO-4H-THIENO 3,2-C PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | Merck Generics (UK) Limited (GB) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035652-A9 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS UK LTD (GB) | 2004-04-08 | — | — | WO | disclosed |
| WO-2003035652-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS [UK] LIMITED (GB) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049415-A1 | Process for preparing enantiomerically pure alpha phenyl-alpha (6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)-acetic acid derivatives | NR1H3, NR1H2, NR1H4 | DRD1 835/4885CYP2C19 124/4885DRD4 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.