Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL2577871 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2CYP2D6LTA4H | |
| SCHEMBL4051907 | 0.88 | LTA4H (0.46) | CYP2D6LTA4HENPP2POLBHRH3 | |
| SCHEMBL2578648 | 0.88 | LTA4H (0.46) | CYP2D6LTA4HENPP2POLBHRH3 | |
| SCHEMBL1385958 | 0.88 | LTA4H (0.46) | CYP2D6LTA4HENPP2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL2575663 | 0.87 | LTA4H (0.45) | CYP2D6LTA4HENPP2POLBHRH3 | |
| SCHEMBL1384547 | 0.83 | PDE10A (0.42) | KDM4ECYP2D6LTA4HPOLBHRH3 | |
| Hydrochloric Acid SCHEMBL2575915 | 0.82 | POLB (0.42) | KDM4ECYP2D6LTA4HPOLBHRH3 | |
| SCHEMBL1385049 | 0.78 | PDE10A (0.43) | KDM4ECYP2D6ENPP2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL2577843 | 0.77 | PDE10A (0.42) | KDM4ECYP2D6ENPP2POLBHRH3 | |
| Oxalic Acid SCHEMBL2582750 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165005-A1 | Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2005-07-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165005-A1 | Pyrazolyl derivatives, preparation process and intermediates of this process as medicinal products and pharmaceutical compositions containing them | C1R, CBR3, C3AR1 | KDM4E 4615/4885ALDH1A1 2499/4885SMN1; SMN2 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.