Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505091 | 0.88 | MAOB (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL5807958 | 0.87 | SIRT2 (0.53) | ALDH1A1SIRT2LTA4HPPARGMEN1 | |
| SCHEMBL4344780 | 0.87 | MEN1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4334820 | 0.79 | MRGPRX4 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3502865 | 0.78 | MEN1 (0.58) | ALDH1A1LTA4HMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4346850 | 0.78 | KMT2A (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL680052 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3649956 | 0.76 | FFAR1 (0.48) | MEN1KMT2AMAOB | |
| SCHEMBL6438683 | 0.76 | NR4A2 (0.64) | ALDH1A1LTA4HMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4333146 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511718-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099763-A1 | N-ACYLAMINOBENZENE DERVATIVES AS SELECTIVE MONOAMINE OXIDASE B INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-04 | — | — | WO | disclosed |