Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL452523 | 0.97 | HTR6 (0.58) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL450071 | 0.97 | HTR6 (0.58) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL271868 | 0.94 | HTR6 (0.67) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL524430 | 0.93 | HTR6 (0.59) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL1267270 | 0.92 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL943337 | 0.92 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL451992 | 0.92 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL43171 | 0.92 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL452359 | 0.92 | HTR6 (0.64) | HTR6HPGDKMT2ASMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL4321509 | 0.91 | HTR6 (0.57) | HTR6HPGDKMT2ASMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023166351-A1 | HISTAMINE H3 RECEPTOR ANTAGONIST AND MEDICAL USE THEREOF | 杭州百诚医药科技股份有限公司 | 2023-09-07 | — | — | WO | claimed |
| CN-113200908-A | Tertiary amine-containing anthranilamide compound and preparation and application thereof | 南华大学 | 2021-08-03 | — | — | CN | claimed |
| CN-104470911-B | Urethane/urea derivative | 诺华股份有限公司 | 2018-04-06 | — | — | CN | claimed |
| EP-2440204-B1 | NICOTINAMIDE COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2013-12-18 | — | — | EP | claimed |
| US-8586751-B2 | Nicotinamide compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-11-19 | — | — | US | claimed |
| CN-102458402-B | Nicotinamide compounds useful as kinase modulators | BRISTOL MYERS SQUIBB CO | 2013-10-02 | — | — | CN | claimed |
| CN-102458402-A | Nicotinamide compounds useful as kinase modulators | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | claimed |
| EP-2440204-A1 | NICOTINAMIDE COMPOUNDS USEFUL AS KINASE MODULATORS | Bristol-Myers Squibb Company (US) | 2012-04-18 | — | — | EP | claimed |
| US-20120082702-A1 | NICOTINAMIDE COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL-MEYERS SQUIBB COMPANY | 2012-04-05 | — | — | US | claimed |
| WO-2010144647-A1 | NICOTINAMIDE COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-12-16 | — | — | WO | claimed |
| WO-2010133544-A1 | PIPERAZINE AND AMINOPYRROLIDINE COMPOUNDS AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2010-11-25 | — | — | WO | claimed |
| US-20260048068-A1 | PHENYLUREA DERIVATIVES AND THEIR PHARMACEUTICAL USES | HANGZHOU BIO SINCERITY PHARMA TECH CO LTD (CN) | 2026-02-19 | — | — | US | disclosed |
| EP-4581017-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2025-07-09 | — | — | EP | disclosed |
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| CN-120152975-A | Pyrazolo [1,5-a ] pyridine and imidazo [1,2-a ] pyridine derivatives as FGFR3 inhibitors for the treatment of cancer | 伊莱利利公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |
| EP-0322643-A1 | Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use | BAYER AG (DE) | 1989-07-05 | — | — | EP | disclosed |
| EP-0313974-A1 | N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals | BAYER AG (DE) | 1989-05-03 | — | — | EP | disclosed |
| US-4806539-A | 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acids and antibacterial agents containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0224178-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260048068-A1 | PHENYLUREA DERIVATIVES AND THEIR PHARMACEUTICAL USES | HRH3, HRH2, HRH4 | HTR6 6/4885HPGD 2546/4885KMT2A 1071/4885 |
| US-20120082702-A1 | NICOTINAMIDE COMPOUNDS USEFUL AS KINASE MODULATORS | NADK, BTK, NAMPT | HTR6 3184/4885HPGD 225/4885KMT2A 2299/4885 |
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | HTR6 2385/4885HPGD 3777/4885KMT2A 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.