Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571907 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL5569527 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL5999215 | 0.82 | ALDH1A1 (0.69) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL498669 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL365802 | 0.75 | KDM4E (0.42) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL147273 | 0.75 | KDM4E (0.42) | ALDH1A1GAAKDM4EMAPTHPGD | |
| Acetic Acid SCHEMBL367778 | 0.74 | KDM4E (0.45) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL6420433 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EMAPTHPGD | |
| Methyl Alcohol SCHEMBL6013731 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL1780394 | 0.73 | HDAC1 (0.36) | ALDH1A1GAAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450790-A4 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | MIRAVANT PHARM INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1450790-A2 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | Miravant Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1377274-A2 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | QLT Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2003028628-A2 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | MIRAVANT PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| WO-2002083097-A2 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | QLT INC. (CA) | 2002-10-24 | — | — | WO | disclosed |