Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 0.50 |
| ▸ | DRD2 | P14416 | 14/20 | 0.50 |
| ▸ | DRD3 | P35462 | 14/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729908 | 0.80 | APP (0.50) | DRD4DRD2DRD3 | |
| SCHEMBL4096846 | 0.78 | MAPT (0.42) | GAA | |
| SCHEMBL2095509 | 0.75 | HTR1B (0.64) | DRD4DRD2DRD3 | |
| SCHEMBL23067925 | 0.74 | DRD4 (0.76) | DRD4DRD2DRD3GAATSHR | |
| SCHEMBL304730 | 0.71 | TAAR1 (0.60) | — | |
| SCHEMBL23067930 | 0.70 | DRD2 (0.92) | DRD4DRD2DRD3 | |
| SCHEMBL8938905 | 0.69 | DRD4 (0.91) | DRD4DRD2DRD3GAA | |
| Hydrochloric Acid SCHEMBL8053903 | 0.68 | DRD2 (0.88) | DRD4DRD2DRD3 | |
| SCHEMBL304917 | 0.68 | PRSS1 (0.46) | DRD3TSHR | |
| SCHEMBL10457449 | 0.67 | APP (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |