SCHEMBL642102

SCHEMBL642102

O=C(Cl)c1ccsc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28495546 0.81 CES2 (0.74)
SCHEMBL8182714 0.79 CES2 (1.00)
SCHEMBL2166098 0.79 CES2 (0.71)
SCHEMBL8672795 0.78 CES2 (0.56)
SCHEMBL1629730 0.77
SCHEMBL152166 0.77
SCHEMBL28858515 0.76
SCHEMBL28858510 0.76
SCHEMBL7334475 0.76 CHEK2 (0.53)
SCHEMBL10919674 0.76 LCK (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112707903-A Metal organic coordination compound and preparation method and application thereof 广东省科学院化工研究所 2021-04-27 CN claimed
CN-109134494-B Electroluminescent material containing polar substituent group anthracene derivative and preparation method and application thereof 华南协同创新研究院 2020-06-05 CN claimed
US-10566106-B2 Conjugated polymer coatings and methods for atmospheric plasma deposition thereof THE BOEING COMPANY (US) 2020-02-18 US claimed
CN-109134494-A Electroluminescent material containing polar substituent group anthracene derivative and preparation method and application thereof 华南协同创新研究院 2019-01-04 CN claimed
US-20160049226-A1 CONJUGATED POLYMER COATINGS AND METHODS FOR ATMOSPHERIC PLASMA DEPOSITION THEREOF THE BOEING COMPANY 2016-02-18 US claimed
US-7365094-B2 Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents 4SC AG (DE) 2008-04-29 US claimed
EP-0536231-B1 A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES AND COMPOUNDS OBTAINED FROM SAID PROCESS BOEHRINGER MANNHEIM ITALIA (IT) 1996-10-23 EP claimed
US-5382679-A Process for the preparation of glutathione S-acyl derivatives, compounds obtained from said process and an intermediate useful for the preparation thereof BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1995-01-17 US claimed
US-5371240-A Process for the preparation of pure thiophene derivatives TORCAN CHEMICAL LTD. (CA) 1994-12-06 US claimed
EP-0536231-A1 A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF. BOEHRINGER MANNHEIM ITALIA (IT) 1993-04-14 EP claimed
WO-1992000320-A1 A PROCESS FOR THE PREPARATION OF GLUTATHIONE S-ACYL DERIVATIVES, COMPOUNDS OBTAINED FROM SAID PROCESS AND AN INTERMEDIATE USEFUL FOR THE PREPARATION THEREOF BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1992-01-09 WO claimed
US-20260070903-A1 NOVEL PYRIDO[3,4-D]PYRIMIDIN-8-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING CANCER, COMPRISING SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-12 US disclosed
EP-4232448-B1 AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR Halo Therapeutics Ltd (GB) 2025-05-07 EP disclosed
WO-2025085233-A1 NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2025-04-24 WO disclosed
EP-3956323-B1 OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 Halo Therapeutics Ltd (GB) 2025-03-05 EP disclosed
US-4002641-A DIURETICS, SALURETICS, HYPOTENSIVES BAYER AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed
US-3997542-A 1-(Halogenated-acetyl)-1,2,3,4-tetrahydro-6-quinolinols and esters thereof STERLING DRUG INC. (US) 1976-12-14 US disclosed
US-3979404-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1976-09-07 US disclosed
US-3976654-A FUNGICIDE SYNTEX (U.S.A.) INC. (US) 1976-08-24 US disclosed
US-3946031-A FUNGICIDES SYNTEX INC. (US) 1976-03-23 US disclosed