Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24893888 | 0.85 | GAA (0.45) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL23021109 | 0.80 | ITGB1 (0.43) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL5961034 | 0.80 | ITGB1 (0.43) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL8926311 | 0.80 | ITGB1 (0.42) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL5961033 | 0.80 | ITGB1 (0.43) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL23000202 | 0.80 | ITGB1 (0.43) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL29394719 | 0.80 | ITGB1 (0.43) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL455356 | 0.79 | GAA (0.83) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL29652703 | 0.79 | GAA (0.83) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL29652695 | 0.79 | GAA (0.83) | GAAGLAALDH1A1HPGDABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849256-B1 | AMIDE COMPOUNDS AND USE OF THE SAME | JAPAN TOBACCO INC (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-1304322-A2 | Carboxylic acid compound and use thereof | Japan Tobacco Inc. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6420561-B1 | Amide compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-0849256-A1 | AMIDE COMPOUNDS AND USE OF THE SAME | Japan Tobacco Inc. (JP) | 1998-06-24 | — | — | EP | disclosed |