Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421069 | 0.80 | GAA (0.51) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL24893888 | 0.78 | GAA (0.45) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL6419633 | 0.75 | ALDH1A1 (0.45) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL6419620 | 0.75 | ALDH1A1 (0.44) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL5961012 | 0.74 | GAA (0.41) | GAAGLAALDH1A1HPGDABCC2 | |
| SCHEMBL5961018 | 0.74 | GLA (0.41) | ITGB1ITGA4ITGB7GAAGLA | |
| SCHEMBL5961147 | 0.74 | RAB9A (0.43) | GAAGLAALDH1A1RAB9A | |
| SCHEMBL6423309 | 0.74 | ALDH1A1 (0.45) | GAAGLAALDH1A1HPGDABCC2 | |
| Hydrochloric Acid SCHEMBL5961021 | 0.73 | GLA (0.40) | ITGB1ITGA4ITGB7GAAGLA | |
| Hydrochloric Acid SCHEMBL5961015 | 0.73 | GAA (0.40) | GAAGLAALDH1A1HPGDABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781282-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-02 | — | — | EP | claimed |
| WO-1996008493-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-03-21 | — | — | WO | claimed |
| JP-9124571-A | — | — | None | — | — | JP | disclosed |
| EP-0781282-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-02 | — | — | EP | disclosed |
| JP-H09124571-A | AMIDE AND ITS USE | JAPAN TOBACCO INC | 1997-05-13 | — | — | JP | disclosed |
| WO-1996008493-A1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-03-21 | — | — | WO | disclosed |