SCHEMBL6421752

SCHEMBL6421752

FC(C(F)(F)F)C(F)(F)OC(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10804047 0.77 MEN1 (0.33) MEN1KMT2A
SCHEMBL2525677 0.77 MEN1 (0.33) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL2522793 0.74 ALDH1A1 (0.31) ALDH1A1HSD17B10TSHR
SCHEMBL5171493 0.74
SCHEMBL13170497 0.72 ALDH1A1 (0.31) ALDH1A1HSD17B10TSHR
SCHEMBL2526354 0.72 ALDH1A1 (0.31) ALDH1A1HSD17B10TSHR
SCHEMBL5172158 0.71 ALDH1A1 (0.32) ALDH1A1HSD17B10TSHR
SCHEMBL10053844 0.70
SCHEMBL6764975 0.69 ALDH1A1 (0.34) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL1460118 0.69 MEN1 (0.36) MEN1KMT2AALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3876329-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE Ningde Amperex Technology Limited (CN) 2021-09-08 EP claimed
EP-1277724-B1 Method of preparing monofluoromethyl ethers BAXTER INT (US) 2005-06-29 EP disclosed
CN-1140488-C Method of preparing monofluoromethyl ethers ���Ͽع����޹�˾ 2004-03-03 CN disclosed
EP-1277724-A1 Method of preparing monofluoromethyl ethers BAXTER INTERNATIONAL INC. (a Delaware corporation) (US) 2003-01-22 EP disclosed
CN-1244187-A Method of preparing monofluoromethyl ethers BAXTER INT (US) 2000-02-09 CN disclosed
US-5886239-A Method of preparing monofluoromethyl ethers BAXTER INTERNATIONAL INC. 1999-03-23 US disclosed