Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714073 | 0.84 | POLB (0.85) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL9714077 | 0.84 | POLB (0.85) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL9714422 | 0.76 | POLB (0.73) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL6421886 | 0.76 | POLB (0.58) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL10720343 | 0.75 | ABCB1 (0.74) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL9496264 | 0.74 | POLB (0.85) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL8773665 | 0.74 | POLB (0.85) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL6421566 | 0.74 | PTPN1 (0.56) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| Rh-5849 SCHEMBL1538531 | 0.74 | POLB (1.00) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 | |
| SCHEMBL8426425 | 0.74 | POLB (0.75) | POLBSMN1; SMN2HPGDCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043388-A1 | Oxindole hydrazide modulators of protein tyrosine phosphatases (ptps) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. | 2005-02-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043388-A1 | Oxindole hydrazide modulators of protein tyrosine phosphatases (ptps) | PTPRO, PTPRE, PTPRZ1 | POLB 4789/4885SMN1; SMN2 4885/4885HPGD 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.