Ethylene Glycol

Ethylene Glycol

SCHEMBL6421980

CCCCOCC[O].OCCO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
THRB P10828 1/20 0.52
HTT P42858 1/20 0.52
MAPT P10636 1/20 0.52
CYP3A4 P08684 1/20 0.45
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CES2 O00748 1/20 0.39
HPGD P15428 1/20 0.39
ATM Q13315 1/20 0.37
USP2 O75604 1/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL430713 0.90
SCHEMBL14691204 0.87 TSHR (0.56) TSHRMEN1KMT2ATHRBHTT
SCHEMBL21435850 0.87
SCHEMBL4396859 0.87 TSHR (0.52) TSHRMEN1KMT2ATHRBHTT
SCHEMBL4401307 0.87 TSHR (0.56) TSHRMEN1KMT2ATHRBHTT
SCHEMBL9651726 0.87 TSHR (0.56) TSHRMEN1KMT2ATHRBHTT
SCHEMBL4390801 0.87 TSHR (0.52) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL18784039 0.87 TSHR (0.83) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL30672 0.87 TSHR (0.83) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL4669270 0.85 TSHR (0.79) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050043415-A1 Contaminant-tolerant foaming additive BENCHMARK RESEARCH AND TECHNOLOGY, INC. 2005-02-24 US disclosed
US-20050043206-A1 Mixture containing alkyl ether sulfate, polymer, solvent and stabilizer; low viscosity BENCHMARK RESEARCH AND TECHNOLOGY, INC. 2005-02-24 US disclosed
US-20050037941-A1 Contaminant-tolerant foaming additive BENCHMARK RESEARCH AND TECHNOLOGY, INC. 2005-02-17 US disclosed
US-20030078180-A1 Contaminant-tolerant foaming additive BENCHMARK RESEARCH & TECHNOLOGY, INC. 2003-04-24 US disclosed