Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.62 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | HTR1F | P30939 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561079 | 0.87 | HTR6 (0.52) | HTR6DRD2HTR7 | |
| SCHEMBL3563168 | 0.87 | HTR6 (0.49) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3564779 | 0.87 | HTR6 (0.49) | HTR6 | |
| SCHEMBL3556751 | 0.85 | HTR6 (0.64) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3552073 | 0.84 | HTR6 (0.66) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3563421 | 0.84 | HTR6 (0.76) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3552252 | 0.84 | HTR6 (0.67) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3557031 | 0.84 | HTR6 (0.60) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3564346 | 0.82 | HTR6 (0.58) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3558981 | 0.81 | HTR6 (0.53) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |