Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 20/20 | 0.75 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422046 | 0.97 | HTR7 (0.74) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL7650647 | 0.97 | HTR7 (0.74) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6423342 | 0.96 | HTR7 (0.75) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6421333 | 0.91 | HTR7 (0.68) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6424106 | 0.90 | HTR7 (0.71) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6425780 | 0.89 | HTR7 (0.67) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6421379 | 0.87 | HTR7 (0.67) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6422098 | 0.85 | HTR7 (0.72) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6424239 | 0.85 | HTR7 (0.69) | HTR7HTR2AHTR2CHTR2B | |
| SCHEMBL6424392 | 0.84 | HTR7 (0.71) | HTR7HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057814-B1 | TETRAHYDROBENZINDOLE DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-6498251-B1 | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| EP-1057814-A1 | TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |