Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.61 |
| ▸ | HBB | P68871 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342435 | 0.90 | MEN1 (0.61) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL4330222 | 0.81 | MEN1 (0.66) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL4327673 | 0.79 | MEN1 (0.60) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL14758482 | 0.79 | MEN1 (0.77) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL6422466 | 0.78 | MEN1 (0.63) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL4326101 | 0.76 | KMT2A (1.00) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL28658249 | 0.75 | MEN1 (0.62) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL30628031 | 0.75 | MEN1 (0.62) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL4330074 | 0.75 | MEN1 (0.56) | MEN1KMT2AHTTNPSR1GAA | |
| SCHEMBL4320530 | 0.75 | MEN1 (0.71) | MEN1KMT2AHTTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906203-B1 | Substituted 4H-chromene and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2005-06-14 | — | — | US | disclosed |