Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.38 |
| ▸ | RARG | P13631 | 13/20 | 0.38 |
| ▸ | RARA | P10276 | 12/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422811 | 0.94 | RARA (0.32) | RARBRARGRARACYP26A1HDAC3 | |
| SCHEMBL1406876 | 0.91 | RARB (0.42) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6438580 | 0.89 | RARA (0.38) | RARBRARGRARA | |
| SCHEMBL1406538 | 0.88 | RARB (0.43) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1406537 | 0.88 | RARB (0.43) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6422800 | 0.87 | RARB (0.39) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1406659 | 0.81 | RARB (0.56) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1406662 | 0.81 | RARB (0.56) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6421410 | 0.81 | RARB (0.40) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1406590 | 0.81 | RARB (0.46) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513793-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-03-16 | — | — | EP | claimed |
| WO-2003101928-A1 | NOVEL LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2003-12-11 | — | — | WO | claimed |