SCHEMBL6422889

SCHEMBL6422889

CCCCCCCCCC[Si](C)(C)c1cc(C)c([Si](C)(C)CCCCCCCCCC)cc1C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 10/20 0.41
CNR2 P34972 10/20 0.41
KCNH2 Q12809 1/20 0.35
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
AR P10275 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
DNM1 Q05193 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8154127 1.00 CNR1 (0.41) CNR1CNR2KCNH2TSHRTHRB
SCHEMBL6422510 1.00 CNR1 (0.41) CNR1CNR2KCNH2TSHRTHRB
SCHEMBL6425590 1.00 CNR1 (0.41) CNR1CNR2KCNH2TSHRTHRB
SCHEMBL10153425 0.96 CNR1 (0.39) CNR1CNR2KCNH2TSHRTHRB
SCHEMBL6425186 0.91 AR (0.39) CNR1CNR2AR
SCHEMBL6425873 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL3371651 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL862598 0.83 CNR1 (0.32) CNR1CNR2
SCHEMBL14583849 0.80 CNR1 (0.30) CNR1CNR2
SCHEMBL5703510 0.75 CNR1 (0.38) CNR1CNR2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed