SCHEMBL6425873

SCHEMBL6425873

CCCCCCCCCC[Si](C)(C)c1cc(C)ccc1C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.41
CNR2 P34972 6/20 0.41
TLR8 Q9NR97 4/20 0.36
ACHE P22303 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GRM2 Q14416 2/20 0.35
HTT P42858 1/20 0.34
KCNH2 Q12809 1/20 0.34
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371651 1.00 CNR1 (0.41) CNR1CNR2TLR8ACHEL3MBTL1
SCHEMBL8154127 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL6425590 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL6422889 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL6422510 0.83 CNR1 (0.41) CNR1CNR2KCNH2
SCHEMBL10153425 0.80 CNR1 (0.39) CNR1CNR2KCNH2LMNA
SCHEMBL12972950 0.79 CNR1 (0.37) CNR1CNR2TLR8ACHEL3MBTL1
SCHEMBL2057479 0.77 CNR2 (0.39) CNR1CNR2L3MBTL1HTTALDH1A1
SCHEMBL6425186 0.75 AR (0.39) CNR1CNR2L3MBTL1ALDH1A1LMNA
SCHEMBL16671999 0.74 NR1H2 (0.49) CNR1CNR2L3MBTL1HTTKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed