SCHEMBL6423080

SCHEMBL6423080

C=CC(=O)OCCNC(=O)c1cc(C(=O)NCCOC(=O)C=C)cc(C(=O)NCCOC(=O)C=C)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
ALDH1A1 P00352 5/20 0.46
TP53 P04637 2/20 0.46
HIF1A Q16665 2/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15695718 0.89 NPC1 (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28504974 0.85 SMN1; SMN2 (0.61) ALDH1A1THRBNPSR1HPGDSMN1; SMN2
SCHEMBL16425941 0.84 SMN1; SMN2 (0.46) ALDH1A1THRBNPSR1HPGDSMN1; SMN2
SCHEMBL29315941 0.81 SMN1; SMN2 (0.52) ALDH1A1HIF1ATHRBNPSR1HPGD
SCHEMBL278833 0.79 HDAC1 (0.52) ALDH1A1HPGDKMT2AKDM4ERAB9A
SCHEMBL5663537 0.77 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25784266 0.76 ALDH1A1 (0.41) TSHRALDH1A1NPSR1HPGDSMN1; SMN2
SCHEMBL22051890 0.76 NPC1 (0.41) TSHRALDH1A1TP53NPSR1HPGD
SCHEMBL29316114 0.76 CD274 (0.50) MEN1KMT2ARAB9A
SCHEMBL15639867 0.76 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235107-B1 Photopolymerizable composition FUJIFILM CORP (JP) 2016-11-09 EP disclosed
US-6838222-B2 Recording negatives; lithography printing plates; mixture of addiiton polymer and binder FUJI PHOTO FILM CO., LTD. (JP) 2005-01-04 US disclosed
US-20020160295-A1 Recording negatives; lithography printing plates; mixture of addiiton polymer and binder FUJIFILM CORPORATION (JP) 2002-10-31 US disclosed
EP-1235107-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 2002-08-28 EP disclosed