Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107826 | 0.86 | AVPR1A (0.57) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL20382772 | 0.83 | AVPR1A (0.66) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL19189883 | 0.82 | AVPR1A (0.65) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5094961 | 0.81 | AVPR1A (0.64) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5102063 | 0.80 | AVPR1A (0.80) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5098038 | 0.80 | AVPR1A (0.69) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL5094751 | 0.78 | AVPR1A (1.00) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL14801989 | 0.78 | AVPR1A (0.60) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL14801823 | 0.78 | AVPR1A (0.60) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL14802058 | 0.78 | AVPR1A (0.62) | AVPR1AKCNH2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597260-A1 | TRIAZOLE COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004074291-A1 | TRIAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2004-09-02 | — | — | WO | disclosed |