Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9888221 | 0.88 | TDP1 (0.55) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL16576962 | 0.86 | TDP1 (0.53) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL11793193 | 0.84 | TDP1 (0.52) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL29199324 | 0.83 | TDP1 (0.64) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Hydrogen Peroxide SCHEMBL28474133 | 0.83 | TDP1 (0.64) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Hydrogen Peroxide SCHEMBL28425777 | 0.83 | TDP1 (0.64) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL1953844 | 0.83 | TSHR (0.59) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL1786261 | 0.83 | TSHR (0.59) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL260960 | 0.83 | TDP1 (0.64) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL15304709 | 0.81 | TSHR (0.49) | TSHRTDP1ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150275268-A1 | STABILISATION OF BIOLOGICAL SAMPLES | QIAGEN GMBH (DE) | 2015-10-01 | — | — | US | disclosed |
| US-6921633-B2 | Methods and compositions for the preservation of cells, tissues or organs in the vitreous state | BIOLIFE SOLUTIONS INCORPORATED (US) | 2005-07-26 | — | — | US | disclosed |
| US-6310273-B1 | AMPLIFIYING DISEASE RESISTANCE IN PLANTS; TRANSFORMING PLANT, EXPRESS GENE OF INTEREST, MONITOR PLANT FOR RESISTANCE TO DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-30 | — | — | US | disclosed |
| WO-2000009664-A9 | INHIBITING APOPTOSIS IN PLANTS USING A CASPASE INHIBITOR | UNIV CALIFORNIA (US) | 2000-09-08 | — | — | WO | disclosed |
| WO-2000009664-A1 | INHIBITING APOPTOSIS IN PLANTS USING A CASPASE INHIBITOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-24 | — | — | WO | disclosed |