Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622960 | 0.93 | TRPV1 (0.37) | TRPV1TRPA1SPHK1TDP1LMNA | |
| SCHEMBL16460136 | 0.88 | TRPV1 (0.34) | TRPV1TRPA1SPHK1TDP1PTPN1 | |
| SCHEMBL4954833 | 0.83 | TRPV1 (0.42) | TRPV1TRPA1SPHK1TDP1LMNA | |
| SCHEMBL18038633 | 0.83 | TRPV1 (0.48) | TRPV1TRPA1SPHK1TDP1LMNA | |
| SCHEMBL13447458 | 0.82 | TDP1 (0.40) | TRPA1TDP1ALDH1A1TSHR | |
| SCHEMBL15484184 | 0.82 | TDP1 (0.40) | TRPA1TDP1ALDH1A1TSHR | |
| SCHEMBL9317504 | 0.82 | TRPA1 (0.38) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| SCHEMBL3399170 | 0.82 | TRPV1 (0.41) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| SCHEMBL11508064 | 0.81 | TRPV1 (0.46) | TRPV1TRPA1SPHK1TDP1LMNA | |
| SCHEMBL2487460 | 0.80 | TRPA1 (0.41) | TRPV1TRPA1SPHK1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208130-B1 | PREPARATION OF POLY(TRIMETHYLENE TEREPHTHALATE) | DU PONT (US) | 2005-03-02 | — | — | EP | disclosed |