Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229972 | 0.82 | LTA4H (0.49) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL227766 | 0.82 | LTA4H (0.49) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL228974 | 0.81 | LTA4H (0.54) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL227713 | 0.80 | LTA4H (0.48) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL226148 | 0.80 | LTA4H (0.48) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL228940 | 0.80 | ESR1 (0.58) | LTA4HESR1ESR2HRH3 | |
| SCHEMBL226484 | 0.80 | ESR1 (0.58) | LTA4HESR1ESR2HRH3 | |
| SCHEMBL227374 | 0.80 | LTA4H (0.47) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL227373 | 0.80 | LTA4H (0.47) | LTA4HESR1ESR2HRH3MAOB | |
| SCHEMBL4419894 | 0.79 | LTA4H (0.48) | LTA4HESR1ESR2HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |