Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427701 | 0.83 | CTSL (0.49) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL6424293 | 0.83 | CTSL (0.49) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL27629823 | 0.83 | CTSL (0.49) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL4192198 | 0.83 | CTSL (0.49) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL6294320 | 0.82 | CTSL (0.53) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL13885550 | 0.82 | CTSL (0.53) | CTSLCTSKCTSBELANEPREP | |
| SCHEMBL8168155 | 0.80 | CMA1 (0.61) | CTSLCTSKCTSBELANECMA1 | |
| SCHEMBL4445986 | 0.80 | CMA1 (0.61) | CTSLCTSKCTSBELANECMA1 | |
| SCHEMBL17378396 | 0.80 | CMA1 (0.61) | CTSLCTSKCTSBELANECMA1 | |
| SCHEMBL13258959 | 0.80 | CMA1 (0.51) | CTSLCTSKCTSBELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534678-A1 | PLEUROMUTILIN DERIVATIVES AS ANTIMICROBBIALS | Sandoz AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004011431-A1 | PLEUROMUTILIN DERIVATIVES AS ANTIMICROBBIALS | SANDOZ AG (CH) | 2004-02-05 | — | — | WO | disclosed |