Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 8/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22916009 | 0.82 | NPC1 (0.47) | — | |
| SCHEMBL15490068 | 0.82 | POLB (0.37) | — | |
| SCHEMBL22915949 | 0.81 | NPC1 (0.51) | TDP1HPGD | |
| SCHEMBL22915890 | 0.78 | KDM4E (0.47) | HPGD | |
| SCHEMBL15492450 | 0.78 | CREBBP (0.47) | — | |
| SCHEMBL4154205 | 0.78 | ENPP2 (0.36) | — | |
| SCHEMBL1994788 | 0.77 | NAMPT (0.38) | — | |
| SCHEMBL6421007 | 0.77 | TRPV1 (0.52) | HPGD | |
| Oxalic Acid SCHEMBL6423517 | 0.76 | GRIN2B (0.44) | — | |
| Oxalic Acid SCHEMBL6419287 | 0.75 | GAA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |