SCHEMBL642380

SCHEMBL642380

CCOP(=O)(OCC)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 1/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
HSD17B10 Q99714 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
RECQL P46063 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA5B Q9Y2D0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10958497 0.85 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL917444 0.84 ALDH1A1 (0.51) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL31688384 0.84 ALDH1A1 (0.51) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL18486629 0.80 MEN1 (0.61) MEN1KMT2AALDH1A1LMNACA1
SCHEMBL28135873 0.78 MAPK1 (0.44) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL11050240 0.78 TSHR (0.47) MEN1KMT2AALDH1A1LMNACA1
SCHEMBL9441231 0.76 ALDH1A1 (0.53) MEN1KMT2AALDH1A1TDP1CA1
SCHEMBL18486454 0.76 ALDH1A1 (0.50) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL18486613 0.75 HSD17B10 (0.42) MEN1KMT2AALDH1A1TDP1HSD17B10
SCHEMBL18486615 0.75 HSD17B10 (0.42) MEN1KMT2AALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
EP-2057173-B1 AMIDES AS SPHINGOMYELINE INHIBITORS NOVARTIS AG (CH) 2014-02-26 EP disclosed
US-8119617-B2 aSMase inhibitors NOVARTIS AG (CH) 2012-02-21 US disclosed
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20100022482-A1 aSMase inhibitors NOVARTIS AG (CH) 2010-01-28 US disclosed
EP-2057173-A1 AMIDES AS SPHINGOMYELINE INHIBITORS Novartis AG (CH) 2009-05-13 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
CN-101263175-A Polyester, process for production of polyester, and polyester molded article TOYO BOSEKI (JP) 2008-09-10 CN disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
WO-2008022771-A1 AMIDES AS SPHINGOMYELINE INHIBITORS NOVARTIS AG (CH) 2008-02-28 WO disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed
US-4434108-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1984-02-28 US disclosed
US-4421548-A Herbicidally active 2-substituted 5-penoxyphenylphosphonic acid derivatives CIBA-GEIGY CORPORATION (US) 1983-12-20 US disclosed
US-4420436-A HERBICIDES; PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1983-12-13 US disclosed
US-4391624-A 2-NITRO-2',6'-DICHLORO-4'-TRIFLUOROMETHYL SUBSTITUTED CIBA-GEIGY CORPORATION (US) 1983-07-05 US disclosed
US-4322375-A HERBICIDES; PLANT GROWTH REGULATORS; DESICCANTS CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022482-A1 aSMase inhibitors SMPD1, SMPD3, SMPD2 MEN1 2730/4885KMT2A 1761/4885ALDH1A1 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.