Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986086 | 0.75 | KDM4E (0.33) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL29104904 | 0.75 | KDM4E (0.33) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL23430419 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL7450281 | 0.75 | KDM4E (0.31) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL27274828 | 0.72 | KDM4E (0.33) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| Hydrochloric Acid SCHEMBL27281219 | 0.71 | KDM4E (0.32) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL15174742 | 0.71 | KDM4E (0.45) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL3547581 | 0.71 | KDM4E (0.34) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL9693375 | 0.71 | KDM4E (0.31) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL6005148 | 0.71 | KDM4E (0.31) | ALDH1A1MAPTKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | claimed |