SCHEMBL642397

SCHEMBL642397

CNC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 3/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ LGALS8 O00214 2/20 0.46
▸ MAPT P10636 1/20 0.45
▸ GAA P10253 2/20 0.44
▸ SLC28A3 Q9HAS3 2/20 0.44
▸ TYR P14679 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4394977 1.00 PYGB (0.51) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL23867560 1.00 PYGB (0.51) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL28453329 0.84 PYGB (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL28463195 0.84 PYGB (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL29217350 0.84 PYGB (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL28902343 0.84 PYGB (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL7211096 0.81 PYGB (0.53) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL17523750 0.81 SLC28A3 (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL22047951 0.81 SLC28A3 (0.50) PYGBL3MBTL1LGALS8MAPTGAA
SCHEMBL22026379 0.81 SLC28A3 (0.50) PYGBL3MBTL1LGALS8MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1742962-B1 METHODS AND KITS FOR FOLDING PROTEINS IN THE PRESENCE OF LINEAR OR BRANCHED SUGAR POLYMERS EXPEDEON LTD (GB) 2016-11-23 — — EP disclosed
EP-1749018-B1 METHODS AND KITS FOR STABILISING, PROTECTING AND SOLUBILISING PROTEINS EXPEDEON LTD (GB) 2014-10-22 — — EP disclosed
US-20120115772-A1 CONJUGATION METHOD POLYTHERICS LIMITED (GB) 2012-05-10 — — US disclosed
US-8119615-B2 Incubating in an aqueous solution of a sugar polymer or sugar polymer derivative, such as inulin derivatized with urethane groups; improves yield of native protein in genetic engineering EXPEDEON LIMITED (GB) 2012-02-21 — — US disclosed
US-20080281085-A1 Methods And Kits For Folding Proteins NOVEXIN LIMITED (GB) 2008-11-13 — — US disclosed
US-20080161230-A1 Methods and Kits for Stabilising, Protecting and Solubilising Proteins NOVEXIN LIMITED (GB) 2008-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115772-A1 CONJUGATION METHOD INF2, INHA, ALB PYGB 804/4885L3MBTL1 4492/4885LGALS8 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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