Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367475 | 0.88 | CHRM2 (0.34) | NFKB1NFKB2RELAHDAC1HDAC2 | |
| SCHEMBL23696268 | 0.84 | HSD11B1 (0.40) | PLGPLATLMNANR1H2NFKB1 | |
| SCHEMBL21996669 | 0.84 | HSD11B1 (0.40) | PLGPLATLMNANR1H2NFKB1 | |
| SCHEMBL22849379 | 0.84 | HSD11B1 (0.40) | PLGPLATLMNANR1H2NFKB1 | |
| SCHEMBL9964560 | 0.83 | BTK (0.37) | NFKB1NFKB2RELAHDAC1HDAC2 | |
| SCHEMBL574102 | 0.81 | BTK (0.36) | NFKB1NFKB2RELAHDAC1HDAC2 | |
| SCHEMBL871258 | 0.80 | GAA (0.37) | NFKB1NFKB2RELAHDAC1HDAC2 | |
| SCHEMBL6262075 | 0.79 | BTK (0.39) | PLGPLATLMNA | |
| SCHEMBL30157292 | 0.77 | PLG (0.38) | PLGPLATLMNANR1H2NFKB1 | |
| SCHEMBL15021681 | 0.77 | SLC6A4 (0.32) | PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |