⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977561 | 1.00 | — | — | |
| SCHEMBL681871 | 0.80 | — | — | |
| SCHEMBL29738290 | 0.80 | — | — | |
| SCHEMBL4264233 | 0.80 | — | — | |
| SCHEMBL28136030 | 0.79 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL10714528 | 0.77 | KDM4E (0.39) | — | |
| SCHEMBL8508786 | 0.77 | KDM4E (0.43) | — | |
| SCHEMBL5842338 | 0.76 | APLNR (0.37) | — | |
| SCHEMBL20738688 | 0.76 | — | — | |
| SCHEMBL12955046 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161307-B | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119161307-A | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-113979955-A | Preparation method of heterocyclic ester compound | 河南农业大学 | 2022-01-28 | — | — | CN | claimed |
| CN-104388490-A | Method for producing chiral pyrazinyl ethanol by biological catalysis | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-03-04 | — | — | CN | claimed |
| US-8143408-B2 | N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | claimed |
| US-20100137322-A1 | NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | claimed |
| EP-2158198-A2 | NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| EP-3881048-B1 | DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS | LETAT FRANCAIS REPRESENTE PAR LE MINI DE LINTERIEUR (FR) | 2026-05-06 | — | — | EP | disclosed |
| CN-119161307-B | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119161307-B | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119161307-B | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119161307-A | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-119161307-A | Synthesis method of 1- (2-pyrazinyl) ethanol | 济南悟通生物科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | disclosed |
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4638005-A | ELECTRON CARRIERS IN THE PHOTOENZYMATIC PRODUCTION OF HYDROGEN AND AMMONIA | THE COCA-COLA COMPANY | 1987-01-20 | — | — | US | disclosed |