Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071624 | 0.93 | MEN1 (0.40) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2885173 | 0.86 | MEN1 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2885170 | 0.86 | MEN1 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6254891 | 0.85 | MAPK1 (0.49) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2877194 | 0.83 | MAPK1 (0.57) | KMT2AALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL2877196 | 0.83 | MAPK1 (0.57) | KMT2AALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL2882489 | 0.79 | HTT (0.59) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2882487 | 0.79 | HTT (0.59) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2882765 | 0.75 | DYRK1A (0.52) | HPGDNPC1RAB9ADYRK1A | |
| SCHEMBL12975503 | 0.75 | DYRK1A (0.52) | HPGDNPC1RAB9ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549644-A1 | AZOLIDINONE-VINYL FUSED-BENZENE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004007491-A1 | AZOLIDINONE-VINYL FUSED-BENZENE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-01-22 | — | — | WO | disclosed |