Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885170 | 0.93 | MEN1 (0.53) | MAPK1MEN1KMT2AHPGDPSMD14 | |
| SCHEMBL2885173 | 0.93 | MEN1 (0.53) | MAPK1MEN1KMT2AHPGDPSMD14 | |
| SCHEMBL2877194 | 0.92 | MAPK1 (0.57) | MAPK1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL2877196 | 0.92 | MAPK1 (0.57) | MAPK1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL2882769 | 0.89 | DYRK1A (0.52) | HPGDDYRK1ANPC1RAB9A | |
| SCHEMBL12975503 | 0.89 | DYRK1A (0.52) | HPGDDYRK1ANPC1RAB9A | |
| SCHEMBL2882765 | 0.89 | DYRK1A (0.52) | HPGDDYRK1ANPC1RAB9A | |
| SCHEMBL6424320 | 0.85 | MEN1 (0.41) | MAPK1MEN1KMT2AHPGDPSMD14 | |
| SCHEMBL6385644 | 0.85 | DYRK1A (0.41) | HPGDDYRK1AALDH1A1CYP1A2CLK4 | |
| SCHEMBL12975464 | 0.84 | PIK3CD (0.51) | HPGDDYRK1AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531813-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004006916-A1 | USE OF COMPOUNDS FOR INCREASING SPERMATOZOA MOTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) | 2004-01-22 | — | — | WO | disclosed |